There are
3,040 mi
from San Mateo, CA to Palmetto Bay, FL
That's the driving distance. It would take 2 days 6 hours to go from San Mateo, California to Palmetto Bay, Florida.
The flight distance (direct flight from San Mateo, CA to Palmetto Bay, FL) is 2,581.80 mi.
3,040 mi = 4,892.54 kms