There are
2,769 mi
from San Mateo, CA to Palm Coast, FL
That's the driving distance. It would take 2 days 1 hour to go from San Mateo, California to Palm Coast, Florida.
The flight distance (direct flight from San Mateo, CA to Palm Coast, FL) is 2,410.33 mi.
2,769 mi = 4,455.47 kms