There are
2,139 mi
from San Mateo, CA to Northlake, IL
That's the driving distance. It would take 1 day 12 hours to go from San Mateo, California to Northlake, Illinois.
The flight distance (direct flight from San Mateo, CA to Northlake, IL) is 1,841.18 mi.
2,139 mi = 3.22 kms