There are
2,673 mi
from San Mateo, CA to North Tonawanda, NY
That's the driving distance. It would take 1 day 22 hours to go from San Mateo, California to North Tonawanda, New York.
The flight distance (direct flight from San Mateo, CA to North Tonawanda, NY) is 2,295.13 mi.
2,673 mi = 3.22 kms