There are
2,607 mi
from San Mateo, CA to North Augusta, SC
That's the driving distance. It would take 1 day 21 hours to go from San Mateo, California to North Augusta, South Carolina.
The flight distance (direct flight from San Mateo, CA to North Augusta, SC) is 2,269.23 mi.
2,607 mi = 4,195.79 kms