There are
1,735 mi
from San Mateo, CA to Mesquite, TX
That's the driving distance. It would take 1 day 7 hours to go from San Mateo, California to Mesquite, Texas.
The flight distance (direct flight from San Mateo, CA to Mesquite, TX) is 1,485.42 mi.
1,735 mi = 1.61 kms