There are
2,492 mi
from San Mateo, CA to Mayfield Heights, OH
That's the driving distance. It would take 1 day 19 hours to go from San Mateo, California to Mayfield Heights, Ohio.
The flight distance (direct flight from San Mateo, CA to Mayfield Heights, OH) is 2,174.24 mi.
2,492 mi = 3.22 kms