There are
2,965 mi
from San Mateo, CA to Lake Worth, FL
That's the driving distance. It would take 2 days 5 hours to go from San Mateo, California to Lake Worth, Florida.
The flight distance (direct flight from San Mateo, CA to Lake Worth, FL) is 2,563.64 mi.
2,965 mi = 4,771.50 kms