There are
1,965 mi
from San Mateo, CA to Hannibal, MO
That's the driving distance. It would take 1 day 9 hours to go from San Mateo, California to Hannibal, Missouri.
The flight distance (direct flight from San Mateo, CA to Hannibal, MO) is 1,669.59 mi.
1,965 mi = 1.61 kms