There are
2,760 mi
from San Mateo, CA to Greensboro, NC
That's the driving distance. It would take 2 days to go from San Mateo, California to Greensboro, North Carolina.
The flight distance (direct flight from San Mateo, CA to Greensboro, NC) is 2,334.69 mi.
2,760 mi = 4,441.81 kms