There are
2,159 mi
from San Mateo, CA to Dyer, IN
That's the driving distance. It would take 1 day 13 hours to go from San Mateo, California to Dyer, Indiana.
The flight distance (direct flight from San Mateo, CA to Dyer, IN) is 1,861.81 mi.
2,159 mi = 3.22 kms