There are
2,801 mi
from San Mateo, CA to Daytona Beach, FL
That's the driving distance. It would take 2 days 2 hours to go from San Mateo, California to Daytona Beach, Florida.
The flight distance (direct flight from San Mateo, CA to Daytona Beach, FL) is 2,431.20 mi.
2,801 mi = 3.22 kms