There are
2,272 mi
from San Mateo, CA to Carmel, IN
That's the driving distance. It would take 1 day 15 hours to go from San Mateo, California to Carmel, Indiana.
The flight distance (direct flight from San Mateo, CA to Carmel, IN) is 1,944.23 mi.
2,272 mi = 3.22 kms