There are
2,171 mi
from San Mateo, CA to Carbondale, IL
That's the driving distance. It would take 1 day 13 hours to go from San Mateo, California to Carbondale, Illinois.
The flight distance (direct flight from San Mateo, CA to Carbondale, IL) is 1,801.81 mi.
2,171 mi = 3.22 kms