There are
2,326 mi
from San Mateo, CA to Biloxi, MS
That's the driving distance. It would take 1 day 16 hours to go from San Mateo, California to Biloxi, Mississippi.
The flight distance (direct flight from San Mateo, CA to Biloxi, MS) is 1,967.64 mi.
2,326 mi = 3.22 kms