There are
2,471 mi
from San Marcos, CA to Roanoke, VA
That's the driving distance. It would take 1 day 19 hours to go from San Marcos, California to Roanoke, Virginia.
The flight distance (direct flight from San Marcos, CA to Roanoke, VA) is 2,107.11 mi.
2,471 mi = 3.22 kms