There are
2,682 mi
from San Marcos, CA to Palmetto Bay, FL
That's the driving distance. It would take 1 day 23 hours to go from San Marcos, California to Palmetto Bay, Florida.
The flight distance (direct flight from San Marcos, CA to Palmetto Bay, FL) is 2,265.81 mi.
2,682 mi = 3.22 kms