There are
2,282 mi
from San Marcos, CA to Greeneville, TN
That's the driving distance. It would take 1 day 15 hours to go from San Marcos, California to Greeneville, Tennessee.
The flight distance (direct flight from San Marcos, CA to Greeneville, TN) is 1,952.45 mi.
2,282 mi = 3.22 kms