There are
2,659 mi
from San Marcos, CA to Ephrata, PA
That's the driving distance. It would take 1 day 23 hours to go from San Marcos, California to Ephrata, Pennsylvania.
The flight distance (direct flight from San Marcos, CA to Ephrata, PA) is 2,301.98 mi.
2,659 mi = 4,279.49 kms