There are
1,833 mi
from San Marcos, CA to Clarksdale, MS
That's the driving distance. It would take 1 day 8 hours to go from San Marcos, California to Clarksdale, Mississippi.
The flight distance (direct flight from San Marcos, CA to Clarksdale, MS) is 1,526.67 mi.
1,833 mi = 1.61 kms