There are
1,814 mi
from San Marcos, CA to Clarksdale, MS
That's the driving distance. It would take 1 day 7 hours to go from San Marcos, California to Clarksdale, Mississippi.
The flight distance (direct flight from San Marcos, CA to Clarksdale, MS) is 1,526.67 mi.
1,814 mi = 2,920.05 kms