There are
2,180 mi
from San Leandro, CA to Tupelo, MS
That's the driving distance. It would take 1 day 14 hours to go from San Leandro, California to Tupelo, Mississippi.
The flight distance (direct flight from San Leandro, CA to Tupelo, MS) is 1,875.38 mi.
2,180 mi = 3.22 kms