There are
2,785 mi
from San Leandro, CA to Safety Harbor, FL
That's the driving distance. It would take 2 days 2 hours to go from San Leandro, California to Safety Harbor, Florida.
The flight distance (direct flight from San Leandro, CA to Safety Harbor, FL) is 2,367.87 mi.
2,785 mi = 4,481.43 kms