There are
2,719 mi
from San Leandro, CA to Roanoke, VA
That's the driving distance. It would take 1 day 23 hours to go from San Leandro, California to Roanoke, Virginia.
The flight distance (direct flight from San Leandro, CA to Roanoke, VA) is 2,294.25 mi.
2,719 mi = 4,375.63 kms