There are
2,278 mi
from San Leandro, CA to Picayune, MS
That's the driving distance. It would take 1 day 15 hours to go from San Leandro, California to Picayune, Mississippi.
The flight distance (direct flight from San Leandro, CA to Picayune, MS) is 1,912.44 mi.
2,278 mi = 3.22 kms