There are
2,665 mi
from San Leandro, CA to Irmo, SC
That's the driving distance. It would take 1 day 23 hours to go from San Leandro, California to Irmo, South Carolina.
The flight distance (direct flight from San Leandro, CA to Irmo, SC) is 2,288.53 mi.
2,665 mi = 3.22 kms