There are
2,735 mi
from San Leandro, CA to Hilton Head Island, SC
That's the driving distance. It would take 2 days to go from San Leandro, California to Hilton Head Island, South Carolina.
The flight distance (direct flight from San Leandro, CA to Hilton Head Island, SC) is 2,355.56 mi.
2,735 mi = 3.22 kms