There are
2,686 mi
from San Leandro, CA to Gainesville, FL
That's the driving distance. It would take 2 days to go from San Leandro, California to Gainesville, Florida.
The flight distance (direct flight from San Leandro, CA to Gainesville, FL) is 2,338.29 mi.
2,686 mi = 4,321.95 kms