There are
2,264 mi
from San Francisco, CA to Owensboro, KY
That's the driving distance. It would take 1 day 15 hours to go from San Francisco, California to Owensboro, Kentucky.
The flight distance (direct flight from San Francisco, CA to Owensboro, KY) is 1,916.60 mi.
2,264 mi = 3.22 kms