There are
1,743 mi
from San Francisco, CA to Mesquite, TX
That's the driving distance. It would take 1 day 6 hours to go from San Francisco, California to Mesquite, Texas.
The flight distance (direct flight from San Francisco, CA to Mesquite, TX) is 1,491.85 mi.
1,743 mi = 2,804.31 kms