There are
1,889 mi
from San Clemente, CA to Picayune, MS
That's the driving distance. It would take 1 day 8 hours to go from San Clemente, California to Picayune, Mississippi.
The flight distance (direct flight from San Clemente, CA to Picayune, MS) is 1,644.38 mi.
1,889 mi = 3,039.53 kms