There are
1,640 mi
from San Clemente, CA to Maryville, MO
That's the driving distance. It would take 1 day 4 hours to go from San Clemente, California to Maryville, Missouri.
The flight distance (direct flight from San Clemente, CA to Maryville, MO) is 1,339.78 mi.
1,640 mi = 2,639.03 kms