There are
2,408 mi
from Roanoke, VA to Upland, CA
That's the driving distance. It would take 1 day 18 hours to go from Roanoke, Virginia to Upland, California.
The flight distance (direct flight from Roanoke, VA to Upland, CA) is 2,113.48 mi.
2,408 mi = 3,875.60 kms