There are
1,144 mi
from Roanoke, VA to South Sioux City, NE
That's the driving distance. It would take 21 hours 50 mins to go from Roanoke, Virginia to South Sioux City, Nebraska.
The flight distance (direct flight from Roanoke, VA to South Sioux City, NE) is 942.32 mi.
1,144 mi = 1.61 kms