There are
2,472 mi
from Roanoke, VA to San Marcos, CA
That's the driving distance. It would take 1 day 19 hours to go from Roanoke, Virginia to San Marcos, California.
The flight distance (direct flight from Roanoke, VA to San Marcos, CA) is 2,107.11 mi.
2,472 mi = 3.22 kms