There are
2,514 mi
from Roanoke, VA to Reno, NV
That's the driving distance. It would take 1 day 20 hours to go from Roanoke, Virginia to Reno, Nevada.
The flight distance (direct flight from Roanoke, VA to Reno, NV) is 2,147 mi.
2,514 mi = 3.22 kms