There are
2,416 mi
from Roanoke, VA to Palmdale, CA
That's the driving distance. It would take 1 day 18 hours to go from Roanoke, Virginia to Palmdale, California.
The flight distance (direct flight from Roanoke, VA to Palmdale, CA) is 2,129.54 mi.
2,416 mi = 3.22 kms