Miles between Roanoke, VA and Orangeburg, SC

There are
333 mi
from Roanoke, VA to Orangeburg, SC

That's the driving distance. It would take 6 hours 22 mins to go from Roanoke, Virginia to Orangeburg, South Carolina.

The flight distance (direct flight from Roanoke, VA to Orangeburg, SC) is 266.14 mi.

333 mi = 536.33 kms