There are
2,677 mi
from Roanoke, VA to Manteca, CA
That's the driving distance. It would take 1 day 23 hours to go from Roanoke, Virginia to Manteca, California.
The flight distance (direct flight from Roanoke, VA to Manteca, CA) is 2,243.01 mi.
2,677 mi = 4,307.54 kms