There are
173 mi
from Roanoke, VA to Knightdale, NC
That's the driving distance. It would take 3 hours 43 mins to go from Roanoke, Virginia to Knightdale, North Carolina.
The flight distance (direct flight from Roanoke, VA to Knightdale, NC) is 130.69 mi.
173 mi = 278.59 kms