There are
655 mi
from Roanoke, VA to Kennett, MO
That's the driving distance. It would take 12 hours 3 mins to go from Roanoke, Virginia to Kennett, Missouri.
The flight distance (direct flight from Roanoke, VA to Kennett, MO) is 564.18 mi.
655 mi = 1,053.86 kms