There are
315 mi
from Roanoke, VA to Havre De Grace, MD
That's the driving distance. It would take 6 hours 5 mins to go from Roanoke, Virginia to Havre De Grace, Maryland.
The flight distance (direct flight from Roanoke, VA to Havre De Grace, MD) is 261.15 mi.
315 mi = 506.39 kms