Miles between Roanoke, VA and Greenville, SC

There are
289 mi
from Roanoke, VA to Greenville, SC

That's the driving distance. It would take 5 hours 43 mins to go from Roanoke, Virginia to Greenville, South Carolina.

The flight distance (direct flight from Roanoke, VA to Greenville, SC) is 216.05 mi.

289 mi = 465.18 kms