There are
479 mi
from Roanoke, VA to Endicott, NY
That's the driving distance. It would take 9 hours 13 mins to go from Roanoke, Virginia to Endicott, New York.
The flight distance (direct flight from Roanoke, VA to Endicott, NY) is 392.42 mi.
479 mi = 770.73 kms