There are
389 mi
from Roanoke, VA to Cuyahoga Falls, OH
That's the driving distance. It would take 7 hours 39 mins to go from Roanoke, Virginia to Cuyahoga Falls, Ohio.
The flight distance (direct flight from Roanoke, VA to Cuyahoga Falls, OH) is 279.38 mi.
389 mi = 625.76 kms