There are
689 mi
from Roanoke, VA to Crestwood, MO
That's the driving distance. It would take 13 hours 14 mins to go from Roanoke, Virginia to Crestwood, Missouri.
The flight distance (direct flight from Roanoke, VA to Crestwood, MO) is 575.67 mi.
689 mi = 1,109.08 kms