Miles between Roanoke, VA and Clemson, SC

There are
321 mi
from Roanoke, VA to Clemson, SC

That's the driving distance. It would take 6 hours 26 mins to go from Roanoke, Virginia to Clemson, South Carolina.

The flight distance (direct flight from Roanoke, VA to Clemson, SC) is 241.19 mi.

321 mi = 516.60 kms