There are
516 mi
from Roanoke, VA to Canandaigua, NY
That's the driving distance. It would take 10 hours 21 mins to go from Roanoke, Virginia to Canandaigua, New York.
The flight distance (direct flight from Roanoke, VA to Canandaigua, NY) is 412.69 mi.
516 mi = 830.73 kms