There are
398 mi
from Roanoke, VA to Campbellsville, KY
That's the driving distance. It would take 7 hours 47 mins to go from Roanoke, Virginia to Campbellsville, Kentucky.
The flight distance (direct flight from Roanoke, VA to Campbellsville, KY) is 296.80 mi.
398 mi = 640.16 kms