There are
2,612 mi
from Reno, NV to Sanford, NC
That's the driving distance. It would take 1 day 22 hours to go from Reno, Nevada to Sanford, North Carolina.
The flight distance (direct flight from Reno, NV to Sanford, NC) is 2,225.75 mi.
2,612 mi = 3.22 kms