There are
2,183 mi
from Reno, NV to Picayune, MS
That's the driving distance. It would take 1 day 15 hours to go from Reno, Nevada to Picayune, Mississippi.
The flight distance (direct flight from Reno, NV to Picayune, MS) is 1,804.63 mi.
2,183 mi = 3.22 kms